Why Olive Oil is CRUCIAL for Me to Keep Lean 12 months Spherical (Top Fats Superfood Sequence)

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MUFA, Oleic Acid, OEA

The MUFA, oleic acid, is the principle fatty acid in olive oil. The title, “oleic acid” comes from the Latin, “oleum” which means “oil.” Principally, I’m announcing that EVOO is the unique gangster (OG) of oils.

Oleoylethanolamine (OEA) synthesis: Nutritional oleic acid is transformed into OAE during the two-step “transacylation-phosphodiesterase pathway.” First, oleic acid is transformed into N-oleoyl-phosphatidylethanolamine (NOPE) by means of the enzyme NAT, then NOPE is transformed into OAE by means of the enzyme NAPE-PLD. The synthesis of OEA happens within the small gut, liver, and inside maximum peripheral tissues. Actually, it’s been instructed that the explanation plasma OEA correlates with oleic acid intake isn’t as a result of OEA is being produced within the intestines/liver and being transported, however fairly than OEA can spill over into the bloodstream after being synthesized from oleic acid by means of peripheral tissues.

OEA signaling: OEA binds the transcription issue PPARα, which reasons PPARα to shape a heterodimer with RXR that binds to PPARα reaction components on DNA and will increase the expression of a number of genes, together with the ones fascinated with lipid delivery, β-oxidation, lipoprotein uptake, and so forth. Particularly, PPARα will increase the expression of the fats transporter protein CD36 and uncoupling (fat-browning) protein UCP-2 to extend fats burning. OEA additionally binds the TRPV1 receptor the stimulation of which sends a satiety sign from the intestine to the mind by way of the Vagus nerve. Apparently, it seems that that the cuddle hormone, oxytocin, is essential on this mechanism. The Vagus nerve talks to the nucleus of the solitary tract within the hypothalamus, stimulating oxytocin unlock and inducing satiety.

OEA knockout rats: Rats missing the enzyme, NAPE-LD, that makes OEA from oleic acid show off weight problems, insulin resistance, greater ldl cholesterol and triglycerides, greater irritation, and an impaired fats browning in accordance with chilly.
Development in Lipid Analysis 2017, Evaluation

(For extra on OEA, see oleoylethanolamine file, or ask Nick to resend.)

Polyphenols (Oleocanthal & Hydroxytyrosol)
EVOO comprises a minimum of 36 other antioxidant polyphenols. It’s unimaginable to concisely symbolize some great benefits of all 36, so we will be able to talk about simply two examples: oleocanthal and hydroxytyrosol.

Irritation. Oleocanthal inhibits the pro-inflammatory COX enzymes that give a contribution to a large means of inflammatory sicknesses Nature 2005



Hydorxytyrosol is any other phenolic compound discovered at top ranges in EVOO. It is one of the most powerful antioxidants present in nature, with 10-times the antioxidant energy of green tea.

Subtle olive oils and faux EVOOS include most effective about 10% the hydroxytyrosol as present in true EVOO.

Hydroxytyrosol concentrations in olives range by means of selection. Greek black olives include 100-340 mg/kg, while Greek kalamata olives include 250-750 mg/kg.

Middle. The Eu Food & Protection Authority has said that hydroxytyrosol protects the cardiovascular device and stops atherosclerosis.

Mind. Hydroxytyrosol protects in opposition to Alzheimer’s and Parkinson’s illness by means of crossing the blood-brain barrier and protective the mind’s treasured fat from oxidation.

Most cancers. Intake of fifty µM–100 µM hydroxytyrosol, from EVOO or olives, has been proven to inhibit the expansion of leukemia, adenocarcinoma, colon most cancers, and breast most cancers cells.

Medications 2018

Nicholas Norwitz – Oxford PhD Researcher and Harvard Med Scholar:

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39 thoughts on “Why Olive Oil is CRUCIAL for Me to Keep Lean 12 months Spherical (Top Fats Superfood Sequence)

  1. S. S. says:

    I recently came back to your channel after about more than 1.5 years and everything you say now is opposite of what you used to say back then. You were quite anti-olive oil back then, but now … I understand keto is in research phase and things are supposed to change but it's literally completely opposite of what you used to say

  2. DZ Zhang says:

    Thomas, your information in this video is great for people that want to remain healthy and not at a low bodyfat. Your genetic baseline is at a relatively lower bodyfat percentage therefore you do not have many fat cells that are asking you to eat more. However, for many people, staying lean would make them food obsessed because of ghrelin. Therefore, although olive oil may "satisfy" their nutritional or physical needs, their mind will ask them to eat more and more. Therefore, eating something that is much less calorically dense would make this process easier. For example, if you fed a starving man 100 calories worth of olive oil, they may not even feel like they ate anything. But if you gave them 2 cups of strawberries, they are going to feel much fuller.

  3. Total Body Fitness says:

    I remember watching a news story a while back about an Italian woman who was something like 112 years old and the reporter asked her what her secret was to a long life. She said she drank 8 ounces of extra virgin olive oil per day. Don't think I would recommend taking that much, but goes to show you how healthy it really is! Great video!

  4. leroy richardson says:

    Thomas please please please do videos on how to choose the right apple cider vinegars and omega 3 supplements please. It's really hard to make sure we are getting the good stuff when I don't know what to look for on the labels. It would be nice to know what guidelines to use when choosing my groceries and all that.

  5. S S says:

    Ok so I been consuming coconut oil everyday for the last 31 days I no because I’m on day 31 on keto but anyways am I doing something wrong or bad to my body by consuming coconut oil ?

  6. Dixxi91 says:

    I know these titles are what gets views on YouTube, but I still don't like them xD They're so extravagant they're not true anymore… But I'll get over it, if this is what it takes for you to get more viewers and get the information out there to help thousands of people life healthier, then I'm all for it <3

  7. Be free says:

    Just drizzled some olive oil on my cooked potatoes which was made with 1 tbs coconut oil. For the past 2-3hrs i was just amazed by how full i feel and satiety. So i did some research and they confirmed olive oil makes you full. Usually i wanna snack 1-2 hrs after a meal idk why but not this time. Couldn't even force myself to snack by how comfortable and relaxed by stomach felt. The meal had about 400g potatoes, maybe 50g protein of lean fish, 1tbs coconut oil to cook with and 3-4 teaspoon of olive oil.

  8. Matthew Yates says:

    Can someone send me a link or let me know the company Thomas recommended for Olive Oil. I can can’t find it on any of his videos. Anyone including his team please let me know thank you !

  9. Ellis Garvin says:

    Worry less about nerdy and more about talking super fast while using lots of big, unfamiliar words. I get it that you have tons of energy but slow down man. It makes listening and learning so much easier.

  10. Neeka says:

    I’d love to see a continuation of this video! Im very health cautious and ever since moving to a European country where fresh olive oil is on tap, I’ve wondered if it’s actually good for you. It would be interesting to hear more about how you use it in compound with other foods you eat & how to get the most out of its benefits. Thanks! ☺️

  11. Gaz says:

    If I eat it every day olive oil makes me put weight on no doubt about it despite being a very active person. Coconut oil on the other hand definitely helps make me lose weight probably because of the MCT's. So I prefer coconut oil over the two. It seems to suit me better.

  12. Michaela Rehm says:

    I've been having issues getting calories in on non-fasting days AND my LDL is up AND my liver is acting up… so I started doing shots of olive oil in the mornings on non-fast days and after fast breaking on my fasting days

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